Iran fires missiles at US bases across Middle East after American strikes on nuclear, IRGC sites

Iran launched missile and drone strikes targeting U.S. military facilities in multiple Middle Eastern countries Friday, retaliating after coordinated U.S.-Israeli strikes on Iranian military and nuclear-linked sites.

Explosions were reported in or near areas hosting American forces in Bahrain, Qatar, the United Arab Emirates, Kuwait and Jordan, according to regional officials and state media accounts. Several of those governments said their air defense systems intercepted incoming projectiles.

No U.S. service member fatalities or injuries have been reported yet, a U.S. official told Fox News Digital. U.S. authorities have not publicly released casualty figures or formal damage assessments.

Iran's Islamic Revolutionary Guard Corps (IRGC) described the operation as a direct response to what Tehran called "aggression" against Iranian territory earlier in the day. Iranian officials claimed they targeted U.S. military infrastructure and command facilities.

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The United States military earlier carried out strikes against what officials described as high-value Iranian targets, including IRGC facilities, naval assets and underground sites believed to be associated with Iran's nuclear program. One U.S. official told Fox News that American forces had "suppressed" Iranian air defenses in the initial wave of strikes.

Tomahawk cruise missiles were used in the opening phase of the U.S. operation, according to a U.S. official. The campaign was described as a multi-geographic operation designed to overwhelm Iran's defensive capabilities and could continue for multiple days. Officials also indicated the U.S. employed one-way attack drones in combat for the first time.

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Iran's retaliatory barrage targeted countries that host American forces, including Bahrain - home to the U.S. Navy's Fifth Fleet - as well as Qatar's Al Udeid Air Base and the UAE's Al Dhafra Air Base. Authorities in those nations reported intercepting many of the incoming missiles. At least one civilian was killed in the UAE by falling debris, according to local authorities.

Iranian officials characterized their response as proportionate and warned of additional action if strikes continue. A senior U.S. official described the Iranian retaliation as "ineffective," though independent assessments of the overall impact are still developing.

Regional governments condemned the strikes on their territory as violations of sovereignty, raising the risk that additional countries could become directly involved if escalation continues.

The situation remains fluid, with military and diplomatic channels active across the region. Pentagon officials are expected to provide further updates as damage assessments and casualty reviews are completed.

Fox News' Jennifer Griffin contributed to this report.